ARVD and Sport
Textbook on ARVD
Research in Padua
Often the disease is first diagnosed after the autopsy of a case of sudden
death in a young subject or after thorough clinical examination of a patient
showing arrhytmias. Therefore, the occurrence of the disease appears, at the
first glance, sporadic. On the contrary, in most cases a subsequent study of
the family is able to detect additional subjects showing the typical
features of ARVD.
ARVD is mostly inherited as autosomal dominant trait with incomplete
penetrance. It means that an affected subject has 50% chance to pass the
defective gene to his/her progeny, but the subject who inherited the
defective gene has, in turn, about 70% chance of manifesting the disease at
the clinical level.
The autosomal recessive inheritance is infrequent. To date, this form was
described only in the island of Naxos (Greece), associated with palmoplantar